Glass process equipment / Production


Process equipment for pharmaceutical and chemical production


Glasslined steel reactor with glass overhead for vacuum distillation
AE/BE type glass lined reactors

Glass lined steel reactor: 250 - 10'000 liter
Pressure: -1.0 (FV) to +0.5 bar
Temperature: -60°C (-90°C) to +200°C
Material: Borosilicate glass 3.3 / glass lined steel / PTFE / PFA / Tantalum

Chemical process equipment, consisting of glass lined reactors or mixing tanks with distillation glass overhead are mainly used under vacuum for distillation, reflux distillation for different chemical synthesis and solvent recovery. Our 3-D engineering enables the integration of large glass lined reactors of different suppliers in combination with our glass components, forming a complete reaction system for production scale. Benefit from our long-term experience in the manufacturing of safe and reliable glass process equipment.

Glass lined reactors


  • AE / BE type reactors up to 10'000 liters
  • Different setups are available

Distillation glass overhead


  • Feed vessel for addition of liquids in glass / glass lined steel
  • Glass distillation column
  • Packed glass columns for rectification
  • Column packings such as raschig rings, ceramic saddle packing, structured packing with different separation efficiency in different materials
  • Shell & tube type heat exchanger (glass / SiC) / Spiral (reflux) condenser batteries
  • Reflux divider
  • Receiver vessel for collection of distillate / condensate in glass / glass lined steel
  • Dean stark phase separator for azeotropic distillation
  • Vacuum / pressure equalization and distribution (for semi batch operation)
  • Self-draining «büchiflex» glass piping

Examples


630 liter mixing tank with glass distillation overhead
630 liter mixing tank with glass distillation overhead
DN400 glass shell & tube type heat exchanger
DN400 glass shell & tube type heat exchanger
DN300 vapor line with protective glass coating
DN300 vapor line with protective glass coating
cGMP facility with 800 liter tanks for API production
cGMP facility with 800 liter tanks for API production
Overhead with SiC shell & tube type heat exchangers
Overhead with SiC shell & tube type heat exchangers
1000 liter cryogenic reactor with glass overhead
1000 liter cryogenic reactor with glass overhead
DN400 rectification column
DN400 rectification column
DN400 liquid/liquid extraction column
DN400 liquid/liquid extraction column

Typical applications


  • Vacuum distillation
  • Reflux distillation
  • Azeotropic distillation (phase separation)
  • Evaporation to any desired consistency
  • Multi-component reactions
  • Gas introduction into liquid phase
  • Rectification / stripping
  • Extraction of multi phase mixture
  • Crystallization
  • Refluxing
  • Multiple chemical reactions liquid/liquid, liquid/solid
  • Low temperature chemistry
«büchiflex»

Büchi glass reactors are based on the modular «büchiflex» glass system. This unique flexible glass connection provides:

  • safety
  • economy
  • full tightness
  • clean processes

Büchiflex video


Flash is required!

Summing up